\u5927\u5bb6\u61c9\u8a72\u90fd\u77e5\u9053\u9019\u6b21\u7684COVID-19\u662f\u5c6c\u65bcRNA\u75c5\u6bd2\uff0c\u5176\u4ed6\u6709\u540d\u7684RNA\u75c5\u6bd2\u9084\u5305\u62ec\u611b\u6ecb\u75c5\u75c5\u6bd2HIV\u30012002\u5e74\u51fa\u73fe\u7684SARS\u3001C\u578b\u809d\u708e\u75c5\u6bd2\u7b49\u3002RNA\u75c5\u6bd2\u6709\u8457\u8d85\u9ad8\u7684\u7a81\u8b8a\u7387\uff08mutation rates\uff09\uff0c\u9019\u662f\u4e00\u7a2e\u9069\u8005\u751f\u5b58\u7684\u6982\u5ff5\uff0c\u75c5\u6bd2\u60f3\u8981\u5b58\u6d3b\uff0c\u5c31\u8981\u589e\u5f37\u6bd2\u529b\u548c\u9032\u5316\u3002<\/p>\n\n\n\n
RNA\u75c5\u6bd2\u96a8\u6642\u90fd\u5728\u91cd\u7d44\u8907\u88fd\uff0c\u5c31\u50cf\u7238\u7238\u5abd\u5abd\u751f\u51fa\u4e00\u500b\u5c0f\u5b69\u4e00\u6a23\uff0c\u5c0f\u5b69\u8eab\u4e0a\u6703\u5e36\u6709\u7238\u7238\u548c\u5abd\u5abd\u7684\u57fa\u56e0\uff0c\u4e0d\u6703\u5b8c\u5168\u662f\u5abd\u5abd\uff0c\u4e5f\u4e0d\u5b8c\u5168\u662f\u7238\u7238\u3002\u75c5\u6bd2\u8907\u88fd\u4e5f\u662f\u540c\u6a23\u9053\u7406\uff0c\u56e0\u6b64\uff0c\u82e5\u5728\u91cd\u7d44\u904e\u7a0b\u4e2d\uff0c\u57fa\u56e0\u8b8a\u7570\u6216\u8b93\u751f\u5b58\u529b\u8f03\u5f37\u7684\u57fa\u56e0\u7d50\u5408\uff0c\u5c31\u53ef\u80fd\u8b93\u8907\u88fd\u7684\u75c5\u6bd2\u66f4\u5f37\u5927\uff0c\u53cd\u4e4b\uff0c\u5247\u8b8a\u5f31\u3002<\/p>\n\n\n\n
\u9019\u662f\u6bcf\u5929\u90fd\u5728\u767c\u751f\u7684\u4e8b\u60c5\uff0cCOVID-19\u53ea\u662f\u4f9d\u7167\u75c5\u6bd2\u7684\u751f\u5b58\u65b9\u5f0f\u5728\u7a81\u8b8a\uff0c\u53ea\u4e0d\u904e\u5bbf\u4e3b\uff08\u4f8b\u5982\uff1a\u4eba\u3001\u9f20\u7b49\uff09\uff0c\u5404\u7a2e\u52d5\u7269\u7684\u7a81\u8b8a\u7387\u90fd\u9060\u6bd4\u75c5\u6bd2\u4f86\u7684\u4f4e\uff0c\u6240\u4ee5\uff0c\u7576\u75c5\u6bd2\u8b8a\u5f37\uff0c\u5c0d\u5bbf\u4e3b\u4f86\u8aaa\u901a\u5e38\u662f\u6709\u5bb3\u7684\uff0c\u5bbf\u4e3b\u4f86\u4e0d\u53ca\u8b8a\u7570\u5c31\u53ef\u80fd\u6703\u88ab\u81ea\u7136\u6dd8\u6c70\u3002<\/p>\n\n\n\n
\u7576\u7136\uff0cRNA\u75c5\u6bd2\u4e5f\u53ef\u80fd\u56e0\u70ba\u7a81\u8b8a\u800c\u8b8a\u5f31\uff0c\u6240\u4ee5\uff0c\u4e0d\u662f\u6240\u6709\u7a81\u8b8a\u90fd\u662f\u4e0d\u597d\u7684\u3002\u7a81\u8b8a\u7684\u91cd\u9ede\u4f86\u81ea\u65bc\u57fa\u56e0\u4ea4\u63db\uff0c\u7576\u5b83\u5011\u4ea4\u63db\u5230\u751f\u5b58\u7387\u8f03\u5dee\u7684\u57fa\u56e0\uff0c\u90a3\u9ebc\uff0c\u5c31\u53ef\u80fd\u8b93\u81ea\u5df1\u6ec5\u4ea1\u3002\u6240\u4ee5\uff0c\u9019\u6b21COVID-19\u7684\u7a81\u8b8a\uff0c\u9084\u5f97\u518d\u6301\u7e8c\u5730\u89c0\u5bdf\uff0c\u624d\u77e5\u9053\u4e16\u754c\u53c8\u6703\u767c\u751f\u4ec0\u9ebc\u6539\u8b8a\u3002\u4f46\u56e0\u70ba\u591a\u6578\u7a81\u8b8a\u90fd\u662f\u5c0d\u5bbf\u4e3b\u6709\u5bb3\uff0c\u56e0\u6b64\uff0c\u73fe\u968e\u6bb5\u7684\u9632\u75ab\u9084\u662f\u5fc5\u9808\u7e7c\u7e8c\uff0c\u5426\u5247\uff0c\u6211\u5011\u5b88\u8b77\u597d\u7684\u5bb6\u5712\uff0c\u5728\u79cb\u51ac\u53ef\u80fd\u53c8\u8981\u88ab\u75c5\u6bd2\u6383\u8569\u4e00\u6ce2\u5594\uff01<\/p>\n\n\n\n
COVID-19\u75c5\u6bd2\u7684\u7a81\u8b8a\u5982\u679c\u662f\u7dad\u6301\u7a69\u5b9a\u7684\u611f\u67d3\u7387\u548c\u6b7b\u4ea1\u7387\uff0c\u90a3\u9ebc\uff0c\u5b83\u5c31\u53ef\u80fd\u6703\u8b8a\u6210\u50cf\u6d41\u611f\u75c5\u6bd2\u4e00\u6a23\u7684\u5b58\u5728\uff0c\u9700\u8981\u7b49\u5f85\u85e5\u7269\u548c\u75ab\u82d7\u51fa\u4f86\uff0c\u624d\u80fd\u964d\u4f4e\u6b7b\u4ea1\u7387\uff01<\/p>\n\n\n\n
\u7e3d\u4e4b\uff0c\u8eab\u5728\u6709\u8db3\u5920\u53e3\u7f69\u7684\u53f0\u7063\uff0c\u5927\u5bb6\u4e0d\u8981\u56e0\u70ba\u9b06\u61c8\u4e86\uff0c\u5c31\u4e0d\u6234\u53e3\u7f69\u5537\uff01<\/p>\n\n\n\n
Reference\uff1a<\/p>\n\n\n\n
1. Why are RNA virus mutation rates so damn high?. PLoS Biol. 2018 Aug; 16(8): e3000003 10.1371\/journal.pbio.3000003<\/p>\n\n\n\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
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